Is Tylenol gluten-free?
Looks mostly clean — worth verifying with the maker. Mostly yes — but worth a quick call to the manufacturer for some generics. Of 18 product labels we checked, 10 are clean, 0 are confirmed gluten-free by the maker, and 8 contain an inactive ingredient (typically a source-ambiguous starch) whose botanical origin isn't fully disclosed. None contained confirmed gluten.
Drug context
About Tylenol
Tylenol is a brand name for acetaminophen — the brand-name acetaminophen used for pain and fever. The active ingredient is the same across brand and generic versions, but inactive ingredients (excipients) can differ between manufacturers, which is the whole point of this page.
Why this matters
Different manufacturers, different ingredients
Generics of Tylenol use the same active ingredient, but they aren't required to use the same inactive ingredients. Your pharmacy may switch which manufacturer they dispense between fills, sometimes without telling you. The list below shows each manufacturer's product label as a separate entry, because that's the granularity that actually matters when you're celiac.
The labels
The 18 we checked
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01Actavis worth a call to confirmView source label →
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02Actavis worth a call to confirmView source label →
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03Actavis worth a call to confirmView source label →
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04Actavis worth a call to confirmView source label →
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05Actavis worth a call to confirmView source label →
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06Actavis worth a call to confirmView source label →
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07Actavis worth a call to confirmView source label →
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08Actavis worth a call to confirmView source label →
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09Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · EDETATE DISODIUM · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYL GALLATE · PROPYLENE GLYCOL · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM
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10Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients CROSCARMELLOSE SODIUM · CROSPOVIDONE · FERRIC OXIDE RED · HYDROXYPROPYL CELLULOSE, UNSPECIFIED · MICA · MICROCRYSTALLINE CELLULOSE · POLYVINYL ALCOHOL GRAFT POLYETHYLENE GLYCOL COPOLYMER (3:1; 45000 MW) · POLYVINYL ALCOHOL, UNSPECIFIED · POVIDONE, UNSPECIFIED · SILICON DIOXIDE · STEARIC ACID · TALC · TITANIUM DIOXIDE
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11Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients CROSCARMELLOSE SODIUM · CROSPOVIDONE · FERRIC OXIDE RED · HYDROXYPROPYL CELLULOSE, UNSPECIFIED · MICA · MICROCRYSTALLINE CELLULOSE · POLYVINYL ALCOHOL GRAFT POLYETHYLENE GLYCOL COPOLYMER (3:1; 45000 MW) · POLYVINYL ALCOHOL, UNSPECIFIED · POVIDONE, UNSPECIFIED · SILICON DIOXIDE · STEARIC ACID
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12Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients ALUMINUM OXIDE · CROSCARMELLOSE SODIUM · CROSPOVIDONE (15 MPA.S AT 5%) · FD&C RED NO. 40 · FD&C YELLOW NO. 6 · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL, UNSPECIFIED · POLYVINYL ALCOHOL, UNSPECIFIED · POVIDONE, UNSPECIFIED · TALC · TITANIUM DIOXIDE
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13Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients FD&C RED NO. 40 · FD&C YELLOW NO. 6 · GELATIN, UNSPECIFIED · GLYCERIN · LECITHIN, SOYBEAN · MINERAL OIL · POLYETHYLENE GLYCOL, UNSPECIFIED · POVIDONE, UNSPECIFIED · PROPYLENE GLYCOL · SHELLAC · SORBITOL · TITANIUM DIOXIDE · WATER
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14Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients AMMONIUM GLYCYRRHIZATE · ANHYDROUS CITRIC ACID · EDETATE DISODIUM · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SODIUM BENZOATE · SODIUM CHLORIDE · SODIUM SULFATE ANHYDROUS · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM
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15Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients ALUMINUM OXIDE · CROSPOVIDONE · FD&C RED NO. 40 · FD&C YELLOW NO. 6 · MAGNESIUM STEARATE · MALTODEXTRIN · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL, UNSPECIFIED · POLYVINYL ALCOHOL, UNSPECIFIED · POVIDONE, UNSPECIFIED · SILICON DIOXIDE · STARCH, CORN · STEARIC ACID · TALC · TITANIUM DIOXIDE
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16Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · ANHYDROUS TRISODIUM CITRATE · CORN SYRUP · ETHYLCELLULOSE · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · MALIC ACID · MALTODEXTRIN · PECTIN · POTASSIUM SODIUM TARTRATE · SODIUM CHLORIDE · SODIUM POLYMETAPHOSPHATE · SUCRALOSE · SUCROSE · WATER
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17Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients CROSCARMELLOSE SODIUM · CROSPOVIDONE · HYPROMELLOSE, UNSPECIFIED · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL, UNSPECIFIED · POLYSORBATE 80 · POVIDONE, UNSPECIFIED · TITANIUM DIOXIDE
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18Reckitt Benckiser LLC nothing flagged on the label
Inactive ingredients CROSCARMELLOSE SODIUM · FD&C RED NO. 40 ALUMINUM LAKE · FD&C YELLOW NO. 6 ALUMINUM LAKE · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL, UNSPECIFIED · POLYVINYL ALCOHOL · POVIDONE, UNSPECIFIED · TALC · TITANIUM DIOXIDE
View source label →
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Background
What “gluten in a medication” actually means
Gluten enters drugs through their excipients — the inactive ingredients used to bind, coat, fill, or stabilize the dose. The main concern is wheat starch as a filler. Source-ambiguous starches (plain “starch”, pregelatinized starch, sodium starch glycolate, modified starch) get flagged for verification because their botanical origin isn't always disclosed on the label.
The 2024 Mangione et al. pediatric NDC analysis (689 NDCs across the top 100 pediatric medications) found 1.5% contained gluten outright; another 25.7% couldn't be confirmed either way. Liquid and oral-suspension formulations carry disproportionate risk because wheat starch is a common thickener. Full methodology →
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