Is Tylenol gluten-free?
Looks mostly clean — worth verifying with the maker. Mostly yes — but worth a quick call to the manufacturer for some generics. Of 18 product labels we checked, 10 are clean, 0 are confirmed gluten-free by the maker, and 8 contain an inactive ingredient (typically a source-ambiguous starch) whose botanical origin isn't fully disclosed. None contained confirmed gluten.
Drug context
About Tylenol
Tylenol is a brand name for acetaminophen — the brand-name acetaminophen used for pain and fever. The active ingredient is the same across brand and generic versions, but inactive ingredients (excipients) can differ between manufacturers, which is the whole point of this page.
Why this matters
Different manufacturers, different ingredients
Generics of Tylenol use the same active ingredient, but they aren't required to use the same inactive ingredients. Your pharmacy may switch which manufacturer they dispense between fills, sometimes without telling you. The list below shows each manufacturer's product label as a separate entry, because that's the granularity that actually matters when you're celiac.
The labels
The 18 we checked
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01Actavis worth a call to confirmView source label →
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02Actavis worth a call to confirmView source label →
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03Actavis worth a call to confirmView source label →
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04Actavis worth a call to confirmView source label →
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05Actavis worth a call to confirmView source label →
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06Actavis worth a call to confirmView source label →
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07Actavis worth a call to confirmView source label →
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08Actavis worth a call to confirmView source label →
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09CVS PHARMACY, INC nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · ASCORBIC ACID · D&C YELLOW NO. 10 · EDETATE DISODIUM · FD&C BLUE NO. 1 · GLYCERIN · PROPYL GALLATE · PROPYLENE GLYCOL · SODIUM BENZOATE · SODIUM CITRATE, UNSPECIFIED FORM · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM
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10H E B nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · EDETATE DISODIUM · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYL GALLATE · PROPYLENE GLYCOL · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM
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11CVS HEALTH nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · ASCORBIC ACID · EDETATE DISODIUM · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYL GALLATE · PROPYLENE GLYCOL · SODIUM BENZOATE · SODIUM CITRATE, UNSPECIFIED FORM · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM
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12CVS PHARMACY nothing flagged on the label
Inactive ingredients CITRIC ACID MONOHYDRATE · D&C YELLOW NO. 10 · EDETATE DISODIUM · FD&C BLUE NO. 1 · GLYCERIN · PROPYL GALLATE · PROPYLENE GLYCOL · SODIUM BENZOATE · SODIUM CHLORIDE · SODIUM CITRATE, UNSPECIFIED FORM · SORBITOL · SUCRALOSE · WATER
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13CVS PHARMACY nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · HIGH FRUCTOSE CORN SYRUP · POLYETHYLENE GLYCOL 400 · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER
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14Kenvue Brands LLC nothing flagged on the label
Inactive ingredients D&C YELLOW NO. 10 · FD&C BLUE NO. 1 · FD&C RED NO. 40 · FD&C YELLOW NO. 6 · GELATIN · GLYCERIN · MINERAL OIL · POLYETHYLENE GLYCOL, UNSPECIFIED · POVIDONE · PROPYLENE GLYCOL · WATER
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15Amazon.com Services LLC nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · FD&C YELLOW NO. 6 · GLYCERIN · MENTHOL, UNSPECIFIED FORM · POLYETHYLENE GLYCOL, UNSPECIFIED · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SODIUM CITRATE, UNSPECIFIED FORM · SORBITOL SOLUTION · SUCRALOSE · WATER · XANTHAN GUM
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16CVS PHARMACY nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED · D&C RED NO. 33 · FD&C BLUE NO. 1 · GLYCERIN · MICROCRYSTALLINE CELLULOSE · SODIUM BENZOATE · SORBITOL SOLUTION · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM
View source label → -
17CVS PHARMACY nothing flagged on the label
Inactive ingredients ANHYDROUS CITRIC ACID · CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED · D&C RED NO. 33 · EDETATE DISODIUM · FD&C RED NO. 40 · GLYCERIN · MICROCRYSTALLINE CELLULOSE · SODIUM BENZOATE · SORBITOL SOLUTION · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM
View source label → -
18CVS Pharmacy nothing flagged on the label
Inactive ingredients CROSPOVIDONE, UNSPECIFIED · HYPROMELLOSE, UNSPECIFIED · MICROCRYSTALLINE CELLULOSE · POVIDONE, UNSPECIFIED · PROPYLENE GLYCOL · SODIUM LAURYL SULFATE · SODIUM STARCH GLYCOLATE TYPE A POTATO · STARCH, CORN · STEARIC ACID · TITANIUM DIOXIDE
View source label →
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Background
What “gluten in a medication” actually means
Gluten enters drugs through their excipients — the inactive ingredients used to bind, coat, fill, or stabilize the dose. The main concern is wheat starch as a filler. Source-ambiguous starches (plain “starch”, pregelatinized starch, sodium starch glycolate, modified starch) get flagged for verification because their botanical origin isn't always disclosed on the label.
The 2024 Mangione et al. pediatric NDC analysis (689 NDCs across the top 100 pediatric medications) found 1.5% contained gluten outright; another 25.7% couldn't be confirmed either way. Liquid and oral-suspension formulations carry disproportionate risk because wheat starch is a common thickener. Full methodology →
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