Gluten Screen

DailyMed checked live · reference data updated August 19, 2026 · 18 product labels screened

Is acetaminophen gluten-free?

By

Founder and maintainer of Gluten Screen

Updated October 13, 2026

Not clinically reviewed — verify with your pharmacist

Looks mostly clean — worth verifying with the maker. Mostly yes — but worth a quick call to the manufacturer for some generics. Of 18 product labels we checked, 10 are clean, 0 are confirmed gluten-free by the maker, and 8 contain an inactive ingredient (typically a source-ambiguous starch) whose botanical origin isn't fully disclosed. None contained confirmed gluten.

Drug context

About acetaminophen

Acetaminophen is the common analgesic and antipyretic also marketed as paracetamol, sold under brand names including Tylenol.

Why this matters

Different manufacturers, different ingredients

Generics of acetaminophen use the same active ingredient, but they aren't required to use the same inactive ingredients. Your pharmacy may switch which manufacturer they dispense between fills, sometimes without telling you. The list below shows each manufacturer's product label as a separate entry, because that's the granularity that actually matters when you're celiac.

The labels

The 18 we checked

  1. 01
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 2.5/325 [Actavis] · label dated 2019-04-23

    View source label →
  2. 02
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 2.5/500 [Actavis] · label dated 2019-04-23

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  3. 03
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 5/325 [Actavis] · label dated 2019-04-23

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  4. 04
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 5/500 [Actavis] · label dated 2019-04-23

    View source label →
  5. 05
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 7.5/325 [Actavis] · label dated 2019-04-23

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  6. 06
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 7.5/500 [Actavis] · label dated 2019-04-23

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  7. 07
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 10/325 [Actavis] · label dated 2019-04-23

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  8. 08
    Actavis worth a call to confirm

    Plogsted list · Hydrocodone/Acetaminophen tablet 10/500 [Actavis] · label dated 2019-04-23

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  9. 09
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS DAYQUIL NYQUIL HIGH BLOOD PRESSURE COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN … · label dated Oct 06, 2026

    Inactive ingredients D&C YELLOW NO. 10 · FD&C BLUE NO. 1 · FD&C YELLOW NO. 5 · FD&C YELLOW NO. 6 · GELATIN · GLYCERIN · LECITHIN, SOYBEAN · MICA · POLYETHYLENE GLYCOL, UNSPECIFIED · POLYVINYL ACETATE PHTHALATE · POVIDONE · SORBITOL · TITANIUM DIOXIDE · WATER

    View source label →
  10. 10
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS DAYQUIL AND VICKS NYQUIL COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMI… · label dated Oct 06, 2026

    Inactive ingredients ALCOHOL · CITRIC ACID MONOHYDRATE · FD&C BLUE NO. 1 · FD&C RED NO. 40 · FD&C YELLOW NO. 6 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SODIUM CITRATE · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM

    View source label →
  11. 11
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS PAINQUIL PAIN RELIEVER (ACETAMINOPHEN) LIQUID [THE PROCTER & GAMBLE MANUFACTURING… · label dated Oct 06, 2026

    Inactive ingredients ALCOHOL · ANHYDROUS CITRIC ACID · FD&C RED NO. 40 · POLYSORBATE 20 · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →
  12. 12
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS PAINQUIL AND VICKS PAINQUIL PM PAIN RELIEVER (ACETAMINOPHEN, DIPHENHYDRAMINE HCL)… · label dated Oct 06, 2026

    Inactive ingredients ALCOHOL · ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · POLYSORBATE 20 · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →
  13. 13
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS DAYQUIL KIDS COLD AND COUGH PLUS FEVER (ACETAMINOPHEN, DEXTROMETHORPHAN HBR) LIQU… · label dated Oct 06, 2026

    Inactive ingredients ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →
  14. 14
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS NYQUIL KIDS COLD AND COUGH PLUS FEVER (ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMI… · label dated Oct 06, 2026

    Inactive ingredients ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →
  15. 15
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS NYQUIL ELDERBERRY COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOX… · label dated Oct 06, 2026

    Inactive ingredients ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →
  16. 16
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS NYQUIL COLD AND FLU NIGHTTIME RELIEF (ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMID… · label dated Oct 06, 2026

    Inactive ingredients ALCOHOL · CITRIC ACID MONOHYDRATE · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CITRATE · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM

    View source label →
  17. 17
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS DAYQUIL COLD AND FLU MULTI-SYMPTOM RELIEF (ACETAMINOPHEN, DEXTROMETHORPHAN HYDROB… · label dated Oct 06, 2026

    Inactive ingredients CITRIC ACID MONOHYDRATE · FD&C YELLOW NO. 6 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SODIUM CHLORIDE · SODIUM CITRATE · SORBITOL · SUCRALOSE · WATER · XANTHAN GUM

    View source label →
  18. 18
    The Procter & Gamble Manufacturing Company nothing flagged on the label

    US label (DailyMed) · VICKS DAYQUIL KIDS AND VICKS NYQUIL KIDS COLD AND COUGH PLUS FEVER (ACETAMINOPHEN, DEXT… · label dated Oct 06, 2026

    Inactive ingredients ANHYDROUS CITRIC ACID · FD&C BLUE NO. 1 · FD&C RED NO. 40 · GLYCERIN · PROPYLENE GLYCOL · SACCHARIN SODIUM · SODIUM BENZOATE · SORBITOL · SUCRALOSE · TRISODIUM CITRATE DIHYDRATE · WATER · XANTHAN GUM

    View source label →

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Background

What “gluten in a medication” actually means

Gluten enters drugs through their excipients — the inactive ingredients used to bind, coat, fill, or stabilize the dose. The main concern is wheat starch as a filler. Source-ambiguous starches (plain “starch”, pregelatinized starch, sodium starch glycolate, modified starch) get flagged for verification because their botanical origin isn't always disclosed on the label.

The 2024 Mangione et al. pediatric NDC analysis (689 NDCs across the top 100 pediatric medications) found 1.5% contained gluten outright; another 25.7% couldn't be confirmed either way. Liquid and oral-suspension formulations carry disproportionate risk because wheat starch is a common thickener. Full methodology →

Keep checking

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Important. This page is informational. Drug labels can change without notice; a manufacturer attestation is point-in-time, not a warranty. If you have celiac disease and your pharmacy switches manufacturers, re-screen the new label before taking the dispensed product. For a definitive answer, call the manufacturer's medical-information line with the NDC code from your prescription bottle — or take our printable pharmacist card to the counter, which asks the three questions a pharmacist can actually answer.