Does lisinopril contain wheat or gluten as an excipient?

We cross-check each lisinopril product label against four data sources: DailyMed (FDA Structured Product Labels), the European Medicines Agency centrally-authorised medicines database, the Plogsted curated gluten-free drug list, and the 2024 Mangione et al. pediatric pharmacy NDC analysis. Inactive ingredients are scanned against a 146-entry red-flag dictionary covering wheat, barley, rye, malt, source-ambiguous starches, and FDA gluten-free attestation phrases. At least one manufacturer has formally attested their formulation contains no gluten. Of 12 labels we checked, 2 are confirmed by the maker and 10 show nothing flagged. Confirm the brand or generic on your bottle matches one of the attesting manufacturers below.

Can different manufacturers' generic versions of lisinopril have different gluten status?

Yes. Generics in the United States must use the same active ingredient as the brand, but they are not required to use the same inactive ingredients. Two generics of lisinopril from different manufacturers can use entirely different starch sources, binders, and fillers. A pharmacy may also switch which manufacturer it dispenses between fills without notifying you. Each manufacturer-specific entry below corresponds to a separately-filed product label.

Last verified May 17, 2026 · 12 product labels screened

Is lisinopril gluten-free?

Confirmed gluten-free by at least one manufacturer. At least one manufacturer has formally attested their formulation contains no gluten. Of 12 labels we checked, 2 are confirmed by the maker and 10 show nothing flagged. Confirm the brand or generic on your bottle matches one of the attesting manufacturers below.

Drug context

About lisinopril

Lisinopril is an ACE inhibitor used to treat high blood pressure and heart failure, sold under brand names including Zestril, Prinivil.

Why this matters

Different manufacturers, different ingredients

Generics of lisinopril use the same active ingredient, but they aren't required to use the same inactive ingredients. Your pharmacy may switch which manufacturer they dispense between fills, sometimes without telling you. The list below shows each manufacturer's product label as a separate entry, because that's the granularity that actually matters when you're celiac.

The labels

The 12 we checked

01

Apotex manufacturer-attested gluten-free

Plogsted list · Lisinopril (Apotex, Mylan, Teva, Watson) · label dated 2017-04-28

Listed gluten-free in Plogsted Alpha List (2017-04-28)
View source label →
02

Ranbaxy manufacturer-attested gluten-free

Plogsted list · Lisinopril/HCTZ (Ranbaxy, West-Ward) · label dated 2017-04-28

Listed gluten-free in Plogsted Alpha List (2017-04-28)
View source label →
03

Coupler LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [COUPLER LLC] · label dated May 13, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FERRIC OXIDE RED · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →
04

Coupler LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [COUPLER LLC] · label dated Apr 30, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FERRIC OXIDE RED · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →
05

St. Mary's Medical Park Pharmacy nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [ST. MARY'S MEDICAL PARK PHARMACY] · label dated Apr 17, 2026

Inactive ingredients DIBASIC CALCIUM PHOSPHATE DIHYDRATE · FERRIC OXIDE YELLOW · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · SODIUM STARCH GLYCOLATE TYPE A POTATO · STARCH, CORN
View source label →
06

St Marys Medical Park Pharmacy nothing flagged on the label

US label (DailyMed) · LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLET [ST MARYS MEDICAL PARK PHARMACY] · label dated Mar 12, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FD&C BLUE NO. 2 · MAGNESIUM STEARATE · MANNITOL · STARCH, CORN
View source label →
07

Legacy Pharmaceutical Packaging, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLET [LEGACY PHARMACEUTICAL PACKAGING, LLC] · label dated Mar 09, 2026

Inactive ingredients ALUMINUM OXIDE · ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FD&C BLUE NO. 2 · FERRIC OXIDE RED · FERRIC OXIDE YELLOW · MAGNESIUM STEARATE · MANNITOL · STARCH, CORN
View source label →
08

Legacy Pharmaceutical Packaging, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [LEGACY PHARMACEUTICAL PACKAGING, LLC] · label dated Mar 09, 2026

Inactive ingredients DIBASIC CALCIUM PHOSPHATE DIHYDRATE · FERRIC OXIDE RED · FERRIC OXIDE YELLOW · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →
09

Northwind Health Company, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLET [NORTHWIND HEALTH COMPANY, LLC] · label dated Feb 18, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FERRIC OXIDE RED · MAGNESIUM STEARATE · MANNITOL · STARCH, CORN
View source label →
10

Northwind Health Company, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [NORTHWIND HEALTH COMPANY, LLC] · label dated Feb 13, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FERRIC OXIDE RED · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →
11

Northwind Health Company, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [NORTHWIND HEALTH COMPANY, LLC] · label dated Feb 13, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · FERRIC OXIDE RED · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →
12

Northwind Health Company, LLC nothing flagged on the label

US label (DailyMed) · LISINOPRIL TABLET [NORTHWIND HEALTH COMPANY, LLC] · label dated Feb 13, 2026

Inactive ingredients ANHYDROUS DIBASIC CALCIUM PHOSPHATE · MAGNESIUM STEARATE · MANNITOL · SILICON DIOXIDE · STARCH, CORN
View source label →

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Background

What “gluten in a medication” actually means

Gluten enters drugs through their excipients — the inactive ingredients used to bind, coat, fill, or stabilize the dose. The main concern is wheat starch as a filler. Source-ambiguous starches (plain “starch”, pregelatinized starch, sodium starch glycolate, modified starch) get flagged for verification because their botanical origin isn't always disclosed on the label.

The 2024 Mangione et al. pediatric NDC analysis (689 NDCs across the top 100 pediatric medications) found 1.5% contained gluten outright; another 25.7% couldn't be confirmed either way. Liquid and oral-suspension formulations carry disproportionate risk because wheat starch is a common thickener. Full methodology →

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Important. This page is informational. Drug labels can change without notice; a manufacturer attestation is point-in-time, not a warranty. If you have celiac disease and your pharmacy switches manufacturers, re-screen the new label before taking the dispensed product. For a definitive answer, call the manufacturer's medical-information line with the NDC code from your prescription bottle.